Description
Scans the indicated protein in search of nitration sites
Usage
ni.scan(up_id)
Arguments
up_id a character string corresponding to the UniProt ID.
Value
Returns a dataframe where each row corresponds to a modified residue.
References
Huang et al. Nucleic Acids Res. 2019 47:D298-D308.
See Also
ac.scan(), meto.scan(), p.scan(), gl.scan(), ub.scan(), su.scan(), dis.scan(), sni.scan(), me.scan(), ptm.scan(), reg.scan()
Details
Protein nitration represents a post-translational modification that occurs primarily on tyrosine residues. This modification disrupts nitric oxide signaling and skews metabolism towards pro-oxidant processes.
The package ptm provides a function, ni.scan(), that assists in the identification of nitration sites in a given protein. The UniProt ID of the protein of interest must be passed as argument. For instance, to scan the mouse mitochondrial aspartate aminotransferase (P05202):
ni.scan("P05202")
## up_id organism modification database ## 1 P05202 96 Y96-ni dbPTM
ptm 